|
Granulosa cell tumours (or granulosa-theca cell tumours) are tumours that arise from granulosa cells. These tumours are part of the sex cord-gonadal stromal tumour or non-epithelial group of tumours. Although granulosa cells normally occur only in the ovary, granulosa cell tumours occur in both ovaries and testicles (see Ovarian cancer and Testicular cancer). These tumours should be considered malignant and treated in the same way as other malignant tumours of ovary. The staging system for these tumours is the same as for epithelial tumours and most present as stage I.〔Gynaecology. 3rd Ed. 2003. Churchill Livingstone. PP. 690-691.〕 The peak age at which they occur is 50–55 years, but they may occur at any age. Juvenile granulosa cell tumour is a similar but distinct rare tumour. It too occurs in both the ovary and testis. In the testis it is extremely rare, and has not been reported to be malignant. Although this tumour usually occurs in children (hence its name), it has been reported in adults. ==Clinical presentation== Estrogens are produced by ''functioning'' tumours, and the clinical presentation depends on the patient's age and sex. *Female * * If the patient is postmenopausal, she usually presents with abnormal uterine bleeding. * * If the patient is of reproductive age, she would present with menometrorrhagia. However, in some cases she may stop ovulating altogether. * * If the patient has not undergone puberty, early onset of puberty may be seen. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「granulosa cell tumour」の詳細全文を読む スポンサード リンク
|